Cell surface display of proteins by recombinant host cells

Details Cell surface display of proteins by recombinant host cells Cell surface display of proteins by recombinant host cells

2006-10-24

2006-10-24

Guzo, David (Department: 1633)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S325000

Reexamination Certificate

active

07125973

ABSTRACT:
Methods and vectors are described for expressing recombinant proteins on the surface of host cells. These processes and compositions provide the basis for strategies to produce a fusion protein, comprising a membrane anchor that allows extracellular attachment of the fusion protein in a type II orientation.

REFERENCES:
patent: 6686168 (2004-02-01), Lok
patent: WO98/39476 (1998-11-01), None
Hamann, J. et al., “AICL: a new activation-induced antigen encoded by the human NK gene complex”, 1997, Immunogenetics, vol. 45: pp. 295-300.
Yokoyama-Kobayashi, M., et al. “Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank”, 1999, Gene, vol. 228: pp. 161-167.
Yokoyama-Kobayashi, M., et al. “Signal sequence detection system using secreted protease activity as an indicator”, 1995, Gene, vol. 163, pp. 193-196.

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