Cell separation method and apparatus

Chemistry: analytical and immunological testing – Sedimentation rate or hematocrit

Reexamination Certificate

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Details

C436S177000, C435S325000, C600S580000, C210S513000, C422S051000, C422S918000, C422S939000

Reexamination Certificate

active

08048678

ABSTRACT:
Disclosed herein are apparatus and methods for isolating a fraction of interest from a physiological fluid sample. A sample holder for isolating a fraction of interest from a physiological fluid sample includes a flexible compartment and a rigid exoskeleton that supports the flexible compartment. The flexible compartment may have at least one reservoir with a height to volume ratio of about 0.1 cm/mL to about 5 cm/mL. An automated device for extracting a fraction of interest from the sample includes a sample holder with a flexible compartment supported by a rigid exoskeleton, a support for the sample holder connected to one or more fluid extraction devices, and a motor for moving the extraction device relative to the sample holder. The automated device may include an optical sensor and may include a clamp for clamping the flexible compartment.

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