Cell motility assay

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S243000, C435S283100, C435S325000

Reexamination Certificate

active

06972184

ABSTRACT:
An electrooptical method is disclosed for quantifying the motility response of cells to external stimuli, wherein a target cell population (formed as a function of said response) is subsequently optically differentiated by the addition of an optical differentiation solution, and whereby the targeted cell population becomes more or less detectable to an electrooptical reading device. The method can be used to perform chemotactic assays. For such and other purposes, the method can be performed utilizing high throughput robotic automation.

REFERENCES:
patent: 4535414 (1985-08-01), Lemelson
patent: 5210021 (1993-05-01), Goodwin, Jr.
patent: 5284753 (1994-02-01), Goodwin, Jr.
patent: 5302515 (1994-04-01), Goodwin, Jr.
patent: 5601997 (1997-02-01), Tchao
patent: 5959738 (1999-09-01), Hafeman et al.
patent: 6097025 (2000-08-01), Modlin et al.
patent: 6232608 (2001-05-01), Giebeler et al.
patent: 6236456 (2001-05-01), Giebeler et al.
patent: 6274065 (2001-08-01), Deno et al.
patent: 6313471 (2001-11-01), Giebeler et al.
patent: 6316774 (2001-11-01), Giebeler et al.
patent: 6395505 (2002-05-01), Goodwin, Jr.
patent: 6420183 (2002-07-01), Krahn et al.
patent: 6448030 (2002-09-01), Rust et al.
patent: 6468786 (2002-10-01), Goodwin, Jr.
patent: 2003/0022269 (2003-01-01), Kirk et al.
patent: 0679195 (2003-04-01), None
“Cell Migration Studies with TECAN Systems”, Tecan Corporation Document (dated Sep. 1999) (retrieved from www.tecan.com).
“Analysis of Chemotactic Cell Movement through FATIMA—A Fluorescence Assay for Quantitating Cell Migration In Vitro”, Tecan Corporation Document (undated) (retrieved from www.tecan.com).
“FATIMA—Flurescence-Assisted Transmigration Invasion and Motility Assay”, Tecan Corporation Document (undated) (retrieved from www.tecan.com).
“OCM Chemotaxis 96-Well Cell Migration Assay”, Chemicon Product Literature, Chemicon International, Inc., Revision B: 41266 (Apr. 2002).
L. Karnath et al., “Development of Cancer Cell Invasion Assays in a 96-Well Format”, Millipore Corporation Technical Publication (2001) (retrieved from www.millipore.com).
“Multiscreen—MIC Plates”; Millipore Product User Guide, Millipore Corporation, Rev. B, P36448 (Oct. 2002).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Cell motility assay does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cell motility assay, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cell motility assay will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3506348

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.