Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1992-03-03
1994-03-29
Patterson, Jr., Charles L.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
4352402, 935 66, 935 70, C12N 1506, C12N 516
Patent
active
052984028
ABSTRACT:
The present invention provides cell lines capable of indefinite growth which are produced by transforming leukocytes isolated from peripheral blood of fish with a oncogene, a method of establishing the cell line, a method of recovering immunologically active substances from the culture of the cell lines. It has been difficult to maintain continuous cultures of fish leukocytes. The present invention provides cell lines capable of indefinite growth and a method of producing immunologically active substances, e.g., immunologically acitive substances, using these cell lines.
REFERENCES:
patent: 4652522 (1987-03-01), Kennett et al.
Siegel et al. 1973 in Tissue Culture: methods & applications (ed) Kruse et al. New York: Academic Press pp. 135-138.
American Type Culture Collection Catalogue of Cell Lines and Hybridomas, 7th ed. 1992 see species index pp. 464-477.
Michael G. Reth, Patrizia Ammirati, Sharon Jackson & Frederick W. Alt, "Regulated progression of a cultured pre-B-cell line to the B-cell stage," Nature, vol. 317, Sep. 26, 1985, pp. 353-355.
Kimura Shoji
Murakami Hiroki
Sasamoto Yasuhiko
Sato Nobuyuki
Tamai Tadakazu
Bugaisky G. E.
Patterson Jr. Charles L.
Taiyo Fishery Co. Ltd.
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