Cell line producing feline leukemia virus

Drug – bio-affecting and body treating compositions – Lymphokine

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435235, 435238, 435240, 435241, A61K 3921, C12N 700, C12N 706, C12N 500

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active

046997857

ABSTRACT:
A novel feline fibroblastic cell line infected with Snyder-Theilen feline leukemia virus is provided. The cell line produces large amounts of FeLV when cultured in a medium free from serum supplement. The latter aspect is a substantial advantage since it reduces the expense of culturing and eliminates the need to separate serum from culture medium prior to preparing a vaccine.
Feline fibroblastic cell line FF64/280 was deposited at the American Type Culture Collection on Apr. 17, 1984, and granted accession no. VR 2085.

REFERENCES:
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patent: 4117112 (1978-09-01), Jarrett et al.
patent: 4264587 (1981-04-01), Pedersen et al.
patent: 4303644 (1981-01-01), Davis
patent: 4434157 (1984-02-01), Olsen
Pedersen et al. (1978), Am. J. Vet. Res., 40:1120-1126.
Mathes et al. (1980), by Elsevier/North Holland, Inc., Hardy, Essex and McClelland, eds. Feline Leukemia Virus, vol. No. 4.
Lewis et al. (1981), Infection and Immunity, pp. 888-894.

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