Cell junction PDZ protein

Details Cell junction PDZ protein Cell junction PDZ protein

1998-09-11

1999-09-28

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 435325, 530350, 536 231, 536 235, C12N 1500, C12N 500, C07K 100, C07H 2102

Patent

active

059587318

ABSTRACT:
The invention provides a human cell junction PDZ protein (CJPDZ) and polynucleotides which identify and encode CJPDZ. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CJPDZ.

REFERENCES:
Ponting, C.P. et al., "PDZ domains: targeting signalling molecules to sub-membranous sites", Bioessays, 19: 469-479 (1997).
Simske, J.S. et al., "LET-23 Receptor Localization by the Cell Junction Protein LIN-7 during C. elegans Vulval Induction", Cell, 85: 195-204 (1996).
Simske, J.S. et al., (Direct Submission), GenBank Sequence Database (Accession 1685067), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1685067) 1996.
Simske, J.S. et al., (Direct Submission), GenBank Sequence Database (Accession U78092), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1685066) 1996.

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