Cell induction device

Details Cell induction device Cell induction device

1993-02-12

1997-08-12

Cano, Milton

Chemistry: molecular biology and microbiology

Apparatus

Differentiated tissue perfusion or preservation apparatus

4352831, 435402, 424425, 424484, C12M 300

Patent

active

056564929

ABSTRACT:
The present invention features a device and method for inducing cell differentiation. One embodiment of the present invention features a device comprising a wall having an interior surface and an exterior surface. The interior surface defines a chamber. The exterior surface is capable of being placed in contact with biological tissues. The wall has an opening in communication with the chamber for receiving an induction material and for closing the chamber to contain the induction material. The wall comprises a biologically compatible, permeable material capable of receiving cells capable of differentiation. The device is used to contain an induction material in a biological environment and receiving cells in the chamber. The cells are allowed to differentiate in the presence of the induction material.

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Mizuno et al., "A Collagen/DBP Sponge System Designed for In Vitro Analysis of Chondroinduction", Dec. 4, 1991, Materials Research Society Symposium Proceedings, Tissue-Inducing Biomaterials, vol. 252.
Advertisement for Cellagen Membranes offered by ICN Biomedicals, Inc., Biochemicals Div. of Cleveland, OH.
A Collagen/DBP Sponge System Designed For IN VITRO Analysis Of Chonodroinduction, Mizuno et al. Orthopedic Research, Brigham and Women's Hospital, Harvard Medical School, Boston.

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