Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1981-08-28
1983-11-08
Rosen, Sam
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
424 95, 260112R, A61K 3700, A61K 3556, C07G 700
Patent
active
044142056
ABSTRACT:
Potent cell growth inhibitory substances have been obtained from the Indian Ocean sea hare Dolabella. These substances have been given the names dolastatin 1, dolastatin 2, and dolastatin 3. These compounds are characterized by physical and chemical parameters. Their utility as antiviral agents is supported by the disclosure of various preparations for such use.
REFERENCES:
Pettit et al.-J. of Natural Products vol. 44, No. 4, (1981), pp. 482-485.
Pettit et al.-Chem. Abst. vol. 95, (1981), p. 180,829V.
Makino-Chem. Abst. vol. 77, (1972), p. 98035C.
Eales, N. B., L.M.B.C. Memoirs, vol. XXIV, Proc. and Transactions of the Liverpool Biological Society, vol. XXXV, Session 1920-1921, "Typical British Marine Plants and Animals" in Aplysia, pp. 183-279.
Rosen Sam
Saliwanchik Roman
University Patents Inc.
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