Cell-free Marek's disease virus vaccine

Details Cell-free Marek's disease virus vaccine Cell-free Marek's disease virus vaccine

1993-11-23

1995-01-03

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Combination of antigens from multiple viral species

4352351, 435236, 435237, 4242291, A61K 3912, C12N 708

Patent

active

053784677

ABSTRACT:
The present invention is concerned with a vaccine for the protection of poultry against Marek's Disease. The cell free vaccine of the invention facilitates the handling of the vaccine and reduces the chance of physical abuse. The invention also relates to bivalent or polyvalent vaccines comprising in addition other viruses of the Marek's Disease virus group, i.e. HVT.

REFERENCES:
patent: 4160024 (1979-07-01), Schat et al.
patent: 4895718 (1990-01-01), Witter
Cho "An Improved Method for Extracting Cell-Free Herpesviruses of Marek's Disease and Turkeys from Infected Cell Cultures Avian Diseases" 22(1) 1978, pp. 170-176.
Witter et al "Biological Diversity Among Serotype 2 Marek's Disease Viruses" Avian Diseases 34, 944-957, Oct.-Dec., 1990.
Cook et al "Preparation of Infectious Cell-Free Herpes-Type Virus Associated with Marek's Disease" J. Vir. 5(2) 1970 pp. 258-261.
Calnek et al "Lyophilization of Cell-Free Marek's Disease Herpesvirus and a Herpesvirus from Turkeys" Applied Micorobology, Nov. 1970 (20(5) pp. 723-726.

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