Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-10-01
1999-07-27
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 4352523, 43525233, 43525411, 4352543, 435325, 435419, 536 231, 536 235, C12N 1509, C12N 1570, C12N 1563
Patent
active
059288990
ABSTRACT:
The invention provides three human cell division regulators (HCDR) and polynucleotides which identify and encode HCDR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of HCDR.
REFERENCES:
Genebank Database Accession D50918 "Homo sapiens male myeloblast cell.sub.-- line:KG-1 cDNA to mRNA" Submitted by Nomura et al. Jul. 10, 1997.
N-Geneseq Database Accession Q60527 "Human brain Expressed Sequence Tag EST02533" Submitted by Adams et al. Mar. 16, 1994.
Prelich, G. et al., "Functional identity of proliferating cell nuclear antigen and a DNA polymerase-.delta. auxiliary protein", Nature, 326: 517-520 (1987).
Coxon, A. et al., "Fission yeast cdc21.sub.+ belongs to a family of proteins involved in an early step of chromosome replication", Nucleic Acids Res., 20: 5571-5577 (1992).
Radomski, N. et al., "Molecular Cloning of a Murine cDNA Encoding a Novel Protein, p38-2G4, Which Varies with the Cell Cycle", Exp. Cell Res., 220: 434-445 (1995).
Mori, T. et al., "Isolation and mapping of a human gene (DIFF6) homologous to yeast CDC3, CDC10, CDC11, and CDC12, and mouse Diff6", Cytogenet. Cell Genet., 73: 224-227 (1996).
Longtine, M.S. et al. "The septins: roles in cytokinesis and other processes", Curr. Opin. Cell Biol., 8: 106-119 (1996).
Zieger, B. et al., "Alternative Expression of Platelet Glycoprotein Ib.beta. mRNA from an Adjacent 5' Gene with an Imperfect Polyadenylation Signal Sequence", J. Clin. Invest., 99: 520-525 (1997).
Nagase, T. et al., "Prediction of the Coding Sequences of Unidentified Human Genes. VI. The Coding Sequences of 80 New Genes (KIAA0201-KIAA0280) Deduced by Analysis of cDNA Clones from Cell Line KG-1 and Brain", DNA Res., 3: 321-329 (1996).
Saraste, M. et al., "The P-loop--a common motif in ATP- and GTP-binding proteins", Trends Biochem. Sci., 15: 430-434 (1990).
Kato, K., (Direct Submission), GenBank Sequence Database (Accession 51203), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 51203) No Date Provided.
Kato, K., (Direct Submission), GenBank Sequence Database (Accession X61452), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 51202) No Date Provided.
Ware, J. et al., (Direct Submission), GenBank Sequence Database (Accession 1809317), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1809317) No Date Provided.
Ware, J. et al., (Direct Submission), GenBank Sequence Database (Accession U74628), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1809316) No Date Provided.
Kato, K., (Direct Submission), GenBank Sequence Database (Accession 1469179), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1469179) No Date Provided.
Nagase, T. et al., (Direct Submission), GenBank Sequence Database (Accession D50918), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1469178) No Date Provided.
Nakagawa, Y. et al., (Direct Submission), GenBank Sequence Database (Accession 1167967), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1167967) No Date Provided.
Nakagawa, Y. et al., (Direct Submission), GenBank Sequence Database (Accession U43918), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1167966) No Date Provided.
Bandman Olga
Corley Neil C.
Hillman Jennifer L.
Lal Preeti
Shah Purvi
Incyte Pharmaceuticals Inc.
Mayhew Bradley S.
Wax Robert A.
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