Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form
Reexamination Certificate
2008-07-08
2008-07-08
Davis, Ruth A (Department: 1651)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
C424S443000, C424S444000, C424S093100
Reexamination Certificate
active
10378015
ABSTRACT:
A patch for cardiac tissue engineering includes a gel layer supported by an intermediate layer, which is attached to a reinforcement layer. These patches may be implanted in a heart to treat pediatric congenital malformations of the heart as well as adult ischemic myopathies. The gel layer may include cells such as, for example, stem cells; the intermediate layer may be biodegradable porous mesh and the reinforcement layer may be polytetrafluoroethylene. Included are methods for making patches according to the invention and for tissue engineering using patches of the invention.
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Kreisel Daniel
Krupnick Alexander
Rosengard Bruce R.
Davis Ruth A
The Trustees of the University of Pennsylvania
Woodcock & Washburn LLP
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