Cell death-related nucleases and their uses

Details Cell death-related nucleases and their uses Cell death-related nucleases and their uses

2008-05-06

2008-05-06

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S069100, C435S320100, C435S019000, C530S350000, C530S388260, C536S023200, C536S023500

Reexamination Certificate

active

07368237

ABSTRACT:
An assay uses apoptotic nucleases to screen for apoptosis modulators, in a method of modulating apoptosis, and in a method of aiding in a diagnosis of a disease, among other methods. materials for use in the assay include isolated or recombinant polypeptides and polynucleotides, compositions comprising those isolated or recombinant polypeptides and polynucleotides, vectors, transgenic organisms, and integrated systems among other aspects.

REFERENCES:
patent: 2003/0165863 (2003-09-01), Chiang
Xia et al. Modulation of apoptosis induced by tricyclic antidepressants in human peripheral lymphocytes. J Biochem Mol Toxicol. 1998;12(2):115-23.

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