Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1998-02-27
1999-12-28
Hutzell, Paula K.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 231, 536 2431, 536 243, 530358, 530350, C07H 2104, C07H 2102
Patent
active
060083379
ABSTRACT:
The invention provides human cell cycle related proteins (CCRP) and polynucleotides which identify and encode CCRP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of CCRP.
REFERENCES:
Ciechanover, A., "The Ubiquitin-Proteasome Proteolytic Pathway", Cell, 79: 13-21 (1994).
Stepanova, L. et al., "Mammalian p50.sup.Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4", Genes and Development, 10: 1491-1502 (1996).
Watson, S. And S. Arkinstall, The G-Protein Linked Receptor FactsBook, Academic Press, San Diego, CA, pp. 296-314 (1994).
Watson, J.A. et al., "A Novel Form of the G-Protein .beta. Subunit G.beta..sub.5 Is Specifically Expressed in the Vertebrate Retina", J. Biol. Chem., 271: 28154-28160 (1996).
Tavitian, A., "Proteines RAS et proteines apparentees", C.R. Seances Soc. Biol. Fil., 189: 7-12 (1995).
Benton, B.K. et al., "Over-expression of S. Cerevisiae G.sub.1 cyclins restores the viability of a1g1 N-glycosylation mutants", Curr. Genet., 29: 106-113 (1996).
Stepanova, L. et al., (Direct Submission), GenBank Sequence Database (Accession U43077), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 1375484; GI 1375485) (Jul. 24, 1997).
Benton, B.K. et al., (Direct Submission), GenBank Sequence Database (Accession U19608), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 1292897; GI 1292898; GI 639493) (Jun. 30, 1996).
Daniel, J. et al., (Direct Submission), GenBank Sequence Database (Accession Z14134), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 7344; GI 7345) (Mar. 31, 1995).
Daniel J. et al., "Isolation of two novel ras genes in Dictyostelium discoideum; evidence for a complex, developmentally regulated ras gene subfamily", Oncogene, 9: 501-508 (1994).
Ware, J. and B. Zieger, (Direct Submission), GenBank Sequence Database (Accession U74628), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 1809316; GI 1809317) (Dec. 30, 1997).
Zieger, B. et al., "Alternative Expression of Platelet Glycoprotein Ib.beta. mRNA from an Adjacent 5' Gene with an Imperfect Polyadenylation Signal Sequence", J. Clin. Invest., 99: 520-525 (1997).
Watson, A.J. et al., (Direct Submission), GenBank Sequence Database (Accession U69145), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 1663628; GI 1663269) (Nov. 8, 1996).
Hillier, L. et al., GenBank Sequence Database (Accession R93646), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, Aug. 27, 1995.
Matsubara, K., et al, GenBank Sequence Database (Accession T20314), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, Jul. 18, 1996.
Hillier, L., GenBank Sequence Database (Accession N42988), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, Jan. 25, 1996.
Strausburg, R., GenBank Sequence Database (Accession AA459232), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, Aug. 13, 1997.
Strausburg, R., GenBank Sequence Database (Accession AA557639), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, Aug. 14, 1997.
Watson, A.J., et al., "A Fifth Member of the Mammalian g-Protein Beta-Subunit Family," J. Biol. Chem., vol. 269, No. 35, pp. 22150-22156, Sep. 2, 1994.
Grammatikakis, N., et al., "A Novel Glycosaminoglycan-binding Protein Is the Vertebrate Homologue of the Cell Cycle Control Protein, Cdc37," J. Biol. Chem. vol. 270, No. 27, pp. 16198-16205, Jul. 7, 1995.
Goethals, K., et al., "An Azorhizobium caulinodans ORS571 Locur Involved in Lipopolysaccharide Production and Nodule Formation on Sesbania rostrata Stems and Roots," J. Bacteriol. vol. 176 No. 1, Jan. 1, 1994.
Nottenburg, G., et al., "Lymphocyte HEV adhesion variants differ in the expression of multiple gene sequences," Gene 95, pp. 279-284, Aug. 15, 1990.
Tavitian, A., et al., GenBank Sequence Database (Accession R05076), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, Jul. 10, 1990.
Bandman Olga
Corley Neil C.
Guegler Karl J.
Hillman Jennifer L.
Lal Preeti
Hutzell Paula K.
Incyte Pharmaceuticals Inc.
Muenzen Colette C.
Peterson Sheela Mohan
Worrall Timothy A.
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