Cell cycle regulatory gene

Details Cell cycle regulatory gene Cell cycle regulatory gene

1995-05-12

1998-06-16

Elliot, George C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 235, 435 6, 4351721, 4353201, 435325, 435243, C07H 2102, C07H 2104, C12N 1500, C12N 500

Patent

active

057672580

ABSTRACT:
A novel cell cycle regulatory gene called 5'ALT is disclosed. Methods for determining mutations or polymorphisms in 5'ALT or 5'ALT regulated genes in tissues are also provided. Novel 5'ALT-p16 and 5'ALT-p15 transcripts and truncated expression products are also described.

REFERENCES:
Serrano et al., "A new regulatory motiff in cell-cycle control causing specific inhibition of cyclin D/CDK4", Nature, Dec. 16, 1993, vol. 366, pp. 704-707.

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