Cell cycle regulatory gene

Details Cell cycle regulatory gene Cell cycle regulatory gene

1998-06-16

1999-06-01

Degen, Nancy

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530300, 536 231, 536 234, 536 235, C07K 1400, C07H 2104, C07H 2102

Patent

active

059089202

ABSTRACT:
A novel cell cycle regulatory gene called 5'ALT is disclosed. Methods for determining mutations or polymorphisms in 5'ALT or 5'ALT regulated genes in tissues are also provided. Novel 5'ALT-p16 and 5'ALT-p15 transcripts and truncated expression products are also described.

REFERENCES:
Serrano et al., "A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4", Nature, Dec. 16, 1993, vol. 366, pp. 704-707.

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