Cell culturing method using biomechanical stimulation...

Details Cell culturing method using biomechanical stimulation... Cell culturing method using biomechanical stimulation...

2011-06-28

2011-06-28

Marcheschi, Michael A (Department: 1775)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S177000, C600S036000

Reexamination Certificate

active

07968335

ABSTRACT:
A cell culturing method employing biomechanical stimulation loading and a system for applying, in in vitro culture, stimulation similar to vertical weight load stimulation or sideward shear stress stimulation acting on tissues in an aboveground living body as repeated biomechanical stimulation to culture cells, culture tissues or a construct including the culture cells. The system includes a mechanical stimulation loading device and a culture receptacle that are placed in a carbon dioxide incubator, and a control computer. The device includes a weight loading piston, a piston raising and lowering stage supporting piston to allow vertical movement of a piston within a designated range, and a stage lifting and lowering mechanism for vertically moving the stage. A computer drives the mechanism in a specified cycle to effect the vertical movement of the stage. When the stage is lowered, a culture in the receptacle is weighted with the piston.

REFERENCES:
patent: 5007934 (1991-04-01), Stone
patent: 5622819 (1997-04-01), Herman
patent: 5882929 (1999-03-01), Fofonoff et al.
patent: 6287340 (2001-09-01), Altman et al.
patent: 2004/0147015 (2004-07-01), El-Haj et al.
patent: 11-502715 (1999-03-01), None
patent: 2002-510482 (2002-04-01), None
patent: 2003-265164 (2003-09-01), None
patent: 2004-113222 (2004-04-01), None
patent: 02/051985 (2002-07-01), None

Affiliated with

Also associated with

Rating

Cell culturing method using biomechanical stimulation... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cell culturing method using biomechanical stimulation..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cell culturing method using biomechanical stimulation... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2618956