Cell culture tool and method

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S305300, C435S288300, C435S288400, C435S305100, C435S305200

Reexamination Certificate

active

10751983

ABSTRACT:
A cell co-culture tool includes a body, an outer wall surrounding the body, and more than one vessel within the perimeter of the outer wall. Each vessel has a top edge below a rim of the outer wall.A method of interacting a substance with more than one type of cell material in a culture dish having a plurality of wells includes depositing a different type of the cell material in separate wells of the culture dish, interconnecting the wells with a fluid medium, and adding the substance to the fluid medium.

REFERENCES:
patent: 3826717 (1974-07-01), Gilbert et al.
patent: 4304865 (1981-12-01), O'Brien
patent: 4871674 (1989-10-01), Matsui
patent: 5026649 (1991-06-01), Lyman
patent: 5665596 (1997-09-01), Mussi
Kligerman et al., “Sister chromatid exchange studies in human fibroblast-rat hepatocytes cultures: a new in vitro system to study SCEs”, Environ Mutagen 2:157-165 (1980).
Lyng et al., “Metabolic activation in the fetal mouse salivary gland culture system with rat hepatocytes, rat S-9, and human S-9”, Teratog Carcinog Mutagen 11:31-39 (1991).
Ebron-McCoy et al., “Profile of procarbazine-induced embryotoxicity in an embryo hepatocytes co-culture system”, Teratog Carcinog Mutag 15:33-42 (1995).
El-Mir et al., “In vitro test to determine the effect of cytostatic drugs on co-cultured rat hepatocytes and hepatoma cells”, In J Exp Pathol 79:109-115, (1998).
Mangnum et al., “Co-Culture of Primary Pulmonary Cells to Model Alveolar Injury and Translocation of Protein”, In Vitro. Cell Dev. Biol. 26:1135-1143 (1990).
Wang and Cynade, “Effects of astrocytes on neuronal attachment and survival shown in a serum-free co-culture system,” Brain Res Brain Res Protoc., 4(2):209-16 (1999).
Okamato “Evaluation of the function of primary human hepatocytes co-cultured with the human hepatic stellate cell (HSC) line L190”, Int J Artif Organs, 21(6):353-9 (1998).
Guguen-Guillouzo et al., “Hepatotoxicity and molecular aspects of hepatocyte function in primary culture”, Xenobiotica, 18(6):773-83 (1988).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Cell culture tool and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cell culture tool and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cell culture tool and method will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3799238

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.