Cell culture pumping system

Details Cell culture pumping system Cell culture pumping system

1981-12-24

1983-11-29

Smith, Leonard E.

Pumps

Reverse flow with unidirectional drive or unidirectional...

417383, 417478, 1372695, 13751627, 137534, F04B 2102

Patent

active

044178611

ABSTRACT:
A low trauma, reversible flow pumping system is disclosed which is useful for transfer of biological fluids containing fragile components such as cells. The pumping system comprises a length of collapsible and flexible tubing in fluid communication at each end with a two-way, gravity actuated check valve means having a self-centering, vertically slidable weight member for directional regulation of fluid flow. Said tubing is sealingly enclosed within a hydraulic fluid containing chamber which is in fluid communication with oscillatory pressure providing means to cause alternate expansion and contraction of said tubing.

REFERENCES:
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Bregman et al., Ann. Thoracic Surg. 24 (6), 574-581, (1977). See FIG. 1, p. 575.
Ask et al., Amer. J. Physiol. 233 (5), E389-E396 (1977), See FIG. 1, p. E391 and FIG. 5, p. E392.

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