Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1995-06-02
1998-06-16
Woodward, Michael P.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4242251, 4242041, 4352351, 435236, 435237, A61K 3929, A61K 3912, C12N 704, C12N 708
Patent
active
057666032
ABSTRACT:
Hepatitis A virus is attenuated in virulence by in vitro passage in susceptible cell cultures, without prior passage in a subhuman primate. This process results in a live, attenuated hepatitis A virus vaccine suitable for human disease prevention.
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Giesa Paula A.
Hilleman Maurice R.
Provost Philip J.
Merck & Co. , Inc.
Woodward Michael P.
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