Cell culture of hepatitis A virus

Details Cell culture of hepatitis A virus Cell culture of hepatitis A virus

1993-02-10

1996-05-07

Woodward, Michael P.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

4352351, 435237, A61K 3912, C12N 700, C12N 708

Patent

active

055143768

ABSTRACT:
Hepatitis A virus is attenuated in virulence by in vitro passage in susceptible cell cultures, without prior passage in a subhuman primate. This process results in a live, attenuated hepatitis A virus vaccine suitable for human disease prevention.

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