Cell culture device

Chemistry: molecular biology and microbiology – Apparatus

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435284, 435286, 2103212, 128DIG3, A01N 102

Patent

active

042424593

ABSTRACT:
A cell culture device for use, e.g., as an artificial pancreas, featuring, in various aspects, a tightly wound spiral tube snugly fit in a cavity to form a cell culture compartment, the spiral being eccentrically offset in the cavity to reduce the volume of the compartment, a sloped passage in the body with an end of the tube extending through the passage to the innermost spiral without bending sharply, the ends of the spiral tube communicating with ports on the same side of the body, and a wall of the cavity facing the spiral and being spaced from the tube to form an end of the compartment to provide for simplified cell loading.

REFERENCES:
patent: 3131143 (1964-04-01), Ferrari
patent: 3388803 (1968-06-01), Scott
patent: 3734851 (1973-05-01), Matsumura
patent: 3821087 (1974-06-01), Knazek et al.
patent: 3827565 (1974-08-01), Matsumura
patent: 3883393 (1975-05-01), Knazek et al.
patent: 4144136 (1979-03-01), Corbeil
Whittemore et al., "Effects of the Hybrid Artificial Pancreas in Diabetic Rats", vol. XXIII, Trans. Am. Soc. Artif. Intern. Organs, 1977, pp. 336-340.
Tanishita et al. "Tightly Wound Coils of Microporous Tubing", vol. XXI, Trans. Amer. Soc. Artif. Int. Organs, 1975, pp. 216-223.
Chick et al., "A Hybrid Artificial Pancreas", vol. XXI, Trans. Amer. Soc. Artif. Int. Organs, 1975, pp. 8-14.

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