Cell-cultivation microchamber

Details Cell-cultivation microchamber Cell-cultivation microchamber

2003-08-26

2010-12-07

Beisner, William H (Department: 1797)

Chemistry: molecular biology and microbiology

Apparatus

Bioreactor

C435S287700, C435S287800, C435S288500, C435S305200

Reexamination Certificate

active

07846717

ABSTRACT:
A microchamber including a glass substrate which is transparent to a specific wavelength, an absorbent region which absorbs the specific wavelength, and a melting substance region which does not absorb the specific wavelength, is solid at room temperature and melts when heated, which regions are layered on the glass substrate. The absorbent region, is irradiated with a focused light beam of the specific wavelength and locally heated in the vicinity of the converging rays, so that the melting substance region is locally melted at a portion adjacent to the absorbent region, thereby forming a cavity as the focused light beam moves. Accordingly, the shape of the microchamber can be arbitrarily changed in accordance with the process of cell culture.

REFERENCES:
patent: 2003/0152756 (2003-08-01), Yamada et al.
patent: 8-172956 (1996-07-01), None
patent: 10-191961 (1998-07-01), None
patent: 2001-17155 (2001-01-01), None
patent: 02/42411 (2002-05-01), None
Moriguchi, H.; “An agar-microchamber cell-cultivation system: flexible change of microchamber shapes during cultivation by photo-thermal etching”, May 2002, Lab Chip, 2, 125-130.

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