Cell-based assay for the detection of toxic analytes

Details Cell-based assay for the detection of toxic analytes Cell-based assay for the detection of toxic analytes

2007-05-08

2007-05-08

Gitomer, Ralph (Department: 1657)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

C435S909000

Reexamination Certificate

active

09979699

ABSTRACT:
Cell-based reagents and methods of using the reagents for detecting analytes are provided. The adsorbing of cells with signal-generating metabolic activity to solid supports has been found to improve the sensitivity of known cell based assays. Signal-generating cells adsorbed to a solid support are introduced to a test agent, and the measured decrease in metabolic signal provides a measure of the toxicity of the test agent.

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