Cell adhesion inhibitors

Details Cell adhesion inhibitors Cell adhesion inhibitors

2006-04-25

2006-04-25

Chang, Celia (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S227000

Reexamination Certificate

active

07034043

ABSTRACT:
A cell adhesion inhibitor of the general formula:in-line-formulae description="In-line Formulae" end="lead"?R3-L-L′-R1in-line-formulae description="In-line Formulae" end="tail"?is disclosed. An inhibitor of the present invention interacts with VLA-4 molecules and inhibits VLA-4 dependent cell adhesion. Also disclosed are methods for preparing and using such a cell adhesion inhibitor, as well as pharmaceutical compositions containing the same.

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