CEA immunoassay free of human anti-mouse antibody false positive

Details CEA immunoassay free of human anti-mouse antibody false positive CEA immunoassay free of human anti-mouse antibody false positive

1987-06-01

1990-02-13

Warden, Robert J.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

436548, 436825, 435 7, G01N 33543, G01N 3353

Patent

active

049006843

ABSTRACT:
A CEA immunoassay includes a step for inactivation of interfering human antibodies against non-human immunoglobulin, wherein a buffered serum or plasma sample at about pH 5.0 is heated at about 90.degree. C. for about 15 minutes prior to sandwich assay using capture and probe monoclonals that bind to heat-stable CEA epitopes.

REFERENCES:
patent: 4272504 (1981-06-01), Kim et al.
patent: 4299815 (1981-11-01), Hansen et al.
McLaughlin et al., Clinica Chimica Acta: 130, 199-209 (1983).
Kim et al., Clin. Chem., 25:773-776 (1979).
Hirai, Cancer Research, 37:2267-2274 (Jul. 1977).
Keep et al., VIIth Meeting, International Society for Oncodevelopmental Biology and Medicine, No. 176, p. 14.30 (1970).
Epenetos et al., Brit. J. Radiol., 59:117-125 (1986).

Affiliated with

Also associated with

Rating

CEA immunoassay free of human anti-mouse antibody false positive does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with CEA immunoassay free of human anti-mouse antibody false positive, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and CEA immunoassay free of human anti-mouse antibody false positive will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1167779