cDNAs encoding murine antibody against human plasma apolipoprote

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 711, 43525233, 4353201, 435849, 536 2353, C12N 1500, C12N 1509, C12N 1563, C12N 1570, C12N 100, C12N 120

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060965169

ABSTRACT:
The present invention relates to cDNAs encoding murine antibodies against apolipoprotein B-100, the protein moiety of low density lipoprotein(LDL) in human plasma. In addition, the present invention relates to the method of preparation of recombinant antibodies specific for human plasma apolipoprotein B-100 of LDL, and use thereof, for diagnosis and treatment of cardiovascular diseases.

REFERENCES:
patent: 5420247 (1995-05-01), Gearing et al.
patent: 5541104 (1996-07-01), Chen et al.
patent: 5670132 (1997-09-01), Griffiths et al.
Bachorik et al.; "Apolipoprotein measurements in clinical biochemistry and their utility vis-a-vis conventional assays" Clinica Chimica Acta 178, 1988, pp. 1-34.
Avogaro et al. "Are Apolipoproteins Better Discriminators Than Lipids for Atherosclerosis?", The Lancet, Apr. 28, 1979, pp. 901-903.
Riesen et al., "Apoproteins and Lipids as Discriminators of Severity of Coronary Heart Disease" Atherosclerosis, 37, 1980, pp. 157-162.
De Backer et al., "Discriminative Value of Lipids and Apoproteins in Coronary Heart Disease" Atherosclerosis, 42, 1982, pp. 197-203.
Herbert K. Naito, Ph.D., "The Clinical Significance of Apolipoprotein Measurements", J. of Clinical Immunoassay, vol. 9, No. 1, Spring, 1986, pp. 11-20.
Albers, et al., "Apoprotein Measurements and Their Clinical Application", Clinics in Laboratory Medicine, vol. 9, No. 1, Mar. 1989, pp. 137-152.
R. Rapley, "The Biotechnology and Applications of Antibody Engineering", Molecular Biotechnology, 3, May 1995, pp. 139-154.
N.sub.-- Geneseq.sub.-- 34 T85091, Mar. 17, 1995.
N.sub.-- Geneseq.sub.-- 34 T85090, Mar. 17, 1995.

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