CDNAS coding for members of the carcinoembryonic antigen family

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 6, 935 77, 935 78, C07H 1512, C12Q 168, C12N 1500

Patent

active

051225999

ABSTRACT:
This invention relates to a nucleic acid comprising a base sequence which codes for a CEA family member peptide sequence or nucleic acids having a base sequence hybridizable therewith, replicable recombinant cloning vehicles having an insert comprising such nucleic acid, cells transfected, infected or injected with such cloning vehicles, polypeptides expressed by such cells, synthetic peptides derived from the coding sequence of CEA family member nucleic acids, antibody preparations specific for such polypeptides, immunoassays for detecting CEA family members using such antibody preparations and nucleic acid hybridization methods for detecting CEA family member nucleic acid sequences using a nucleic acid probe comprising the above described nucleic acid.

REFERENCES:
patent: 4228236 (1980-10-01), Jakstys et al.
patent: 4489167 (1984-12-01), Ochi et al.
Gold et al, J. Exp. Med., 121, 439-462 (1965).

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