cDNAs and proteins involved in hypoxia, circadian and orphan...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S023400, C536S023500, C424S093100

Reexamination Certificate

active

07105647

ABSTRACT:
The present invention provides isolated nucleic acids and proteins that are new and distinct members of the bHLH-PAS superfamily of transcription regulators. These “MOPs” (members of PAS) are useful in a variety of research, diagnostic and therapeutic applications. Several of the MOPs of the present invention are α-class hypoxia-inducible factors. Several other of the MOPs of the invention are involved in circadian signal transduction.

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