cDNA of DOCK180 gene and DOCK180 protein

Details cDNA of DOCK180 gene and DOCK180 protein cDNA of DOCK180 gene and DOCK180 protein

1996-01-19

1998-07-07

Ulm, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 651, 4352523, 4353201, 435325, 4353401, 530300, 530350, 536 231, C12N 1512

Patent

active

057770948

ABSTRACT:
The present invention provides a cDNA of DOCK180 gene, which has a nucleotide sequence of SEQ ID NO: 1 and of which translation product binds to the proto-oncogene product CRK, a recombinant vector containing this cDNA, a DOCK180 protein expressed from the EDNA which has a amino acid sequence of SEQ ID NO: 2, and an antibody to the DOCK180 protein. According to the present invention, It is possible to develop new diagnosing and therapeutic techniques using DOCK180 protein and antibody against the protein.

REFERENCES:
Hasegawa et al. (1996) 16:1770-1776.
Matsuda et al. (1996) 271:14468-14472.

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