CDNA fragments corresponding to voltage gated sodium channel gen

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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536 235, 435325, 4352523, 4353201, 530350, C12N 1512, C07K 1447

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active

060602716

ABSTRACT:
The present invention is directed to isolated nucleic acid molecules encoding a voltage gated sodium channel of a peripheral nerve cell, as well as to the isolated voltage gated sodium channels of a peripheral nerve cell encoded thereby. Methods for increasing or decreasing the expression of functional voltage gated sodium channels in host cells are also provided, as well as methods using the sodium channels. Also provided is a method for isolating other voltage gated sodium channels.

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