cDNA fragment coding the alpha interferon receptor gene and proc

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4352523, 43525411, 4353201, 435325, 435361, 536 235, C12N 1512, C07K 14715

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057311692

ABSTRACT:
The invention relates to the human alpha interferon receptor and to the DNA sequence, including the cDNA sequence, encoding the receptor. The invention also relates to non-human cells which express said receptor, to a process for obtaining said cells, and to a process for the preparation of the receptor.

REFERENCES:
Shulman e tal, J. Interferon Res. 8(1) (1988) "Molecular cloning of the human IFN-alpha, beta receptor cDNA", p. S16, abstract No. 3-9.
Revel et al, ICSU Short Reports, vol. 4, 1986 "Interferon receptor and interferon-activated genes", pp. 362-365.
Epstein et al, Biochemical and Biophysical Research Communications, 107(3):1060-1066 (Aug. 16, 1982), Academic Press, Inc. (New York, US) "Direct evidence that the gene product of the human chromosome 21 locus, IFRC, is the interferon-alpha receptor".
Raziuddin et al, Proceedings National Academy Science, vol. 81, Sep. 1984, "Receptors for human alpha and beta interferon but not for gamma interferon are specified by human chromosome 21", pp. 5504-5508.
Uze et al, Cell 60:225-234 (1990).
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Meadows et al, J. Interferon Res. 10(Suppl. 1):5159 (1990).
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