Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2009-03-20
2010-10-26
Shafer, Shulamith H. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
07820792
ABSTRACT:
The present invention provides nucleic acid and polypeptide sequences describing an isoform of the α2δ-4 subunit of a voltage gated calcium channel. The nucleic acids described herein can be used to produce functional α2δ-4 protein. The calcium channel α2δ-4 protein may be isolated for the purposes of binding experiments or may be used in cells to form a functional calcium channel complex.
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Qin, Ning T. et. al: “Molecular Cloning and Characterization of the Human Voltage-Gated Calcium Channel Alpha (2) Delta-4 Subunit.” Molecular Pharmacology. Sep. 2002 pp. 485-496.
Database EMBL Homo Sapiens 12p13.3 PAC PRC15-1096D14, Aug. 4, 1998 XP002313810 retrieved from EMI Database Accession No. AC005342.
Database EMBL Homo Sapiens Chromosome 12 Clone ROP11-76116, Match 17, 2001 XP002313811 retrieved from EBI Database accession No. AC090840.
Database EMBL Homo Sapiens 12 BAC RP11-21K20, Aug. 4, 1998 XP002313812 retrieved from EBI Database Accession No. AC005343.
Database EMBL EST 7h46d04.X1, Dec. 15, 2000, XP 002313813 retrieved from EBI Database Accession No. BF590937.
Codd Ellen
Qin Ning
Ortho-McNeil Pharmaceutical , Inc.
Shafer Shulamith H.
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