Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-01-09
1999-11-02
Teng, Sally
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
536 235, 536 2431, 4352523, 43525411, 4353201, 435325, C12N 1512, C07K 14705
Patent
active
059768347
ABSTRACT:
HNFJD15 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HNFJD15 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.
REFERENCES:
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Colas, J-F. et al., "Drosphila 5-HT.sub.2 serotonin receptor: coexpression with fushi-tarazu during segmentation", Proc. Nat. Acad. Sci. USA, 92:5441-5445, (1995).
Macrae, A.D. et al., "Analysis of the Dopamine Receptor Family in the Compact Genome of the Puffer Fish Fugu rubripes", Genomics, 25:436-446 (1995).
Monsma et al., Mol. Pharmacology, 43, 320-327, 1993.
George et al, Macromolecular Sequencing and Synthesis, 127-149, 127-149, 1988, Alan R. Liss, Inc.
Bergsma Derk John
Ellis Catherine
Fuetterer Wendy S.
Sathe Ganesh Madhusudan
Han William T.
King William T.
SmithKline Beecham Corporation
Teng Sally
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