Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-01-28
2000-03-14
Myers, Carla J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 711, 435455, 435471, 4352523, 4353201, 435 6, 435 912, 536 235, 536 2431, 536 2433, 530350, 530395, C07H 2104, C07K 15705, C12N 1512
Patent
active
060371463
ABSTRACT:
HE8CH90 polypeptides and polynucleotides and method, for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HE8CH90 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain, cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.
REFERENCES:
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Ascension No. Y09479, Moolenaar, et al., Curr. Opin. Cell. Biol. 9(2), 168-173 (1997).
Ascension No. U48235, Macrae et al., Brain Res. Mol. Brain Res. 42(2), 245-254 (1996).
Ascension No. U78192, Moolenaar, et al., Curr. Opin. Cell. Biol. 9(2), 168-173 (1997).
Bergsma Derk
Sathe Ganesh
Han William T.
King William T.
Myers Carla J.
SmithKline Beecham Corporation
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