CDNA clone for T-cell suppressor inducer factor

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 29, 530350, 530351, 530399, C07H 2104

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active

051965267

ABSTRACT:
The invention generally discloses the cloning and characterization of a nucleotide sequence encode for at least a part of primate T-cell suppressor inducer factor (TsFl) protein and in particular, a putative gene for TsFl produced by the murine cell line A.1.1. The nucleotide sequence is 2936 bp in length comprising an encoding sequence 2565 bp in length and encoding a protein of 690 amino acids.

REFERENCES:
patent: 4713332 (1987-12-01), Mak
Hoversland et al., J. Reprod. Res., 88(1), 135-140 (1990).
Ward et al., Nucleic Acids Research, 15(17), 7195 (1987).
Bichko et al., Fed Eur. Biochem. Soc. Lett., 185(1), 208-212 (1985).
Umesono et al., J. Mol. Biol., 203, 299-331 (1988).
R. de Martin et al. "Complementary DNA for human gliobastomia-derived T cell suppressor factor, a novel member of the transforming growth factor-B gene family", The EMBO Journal vol. 6 No. 12 pp. 3673-3677, 1987.
Geoffrey L. Asherson et al. "An Overview of T-Suppressor Cell Circuits", Ann. Rev. Immunol. 1986 4:37-68.

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