Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1991-12-09
1993-06-22
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 235, 530380, C07H 2104, C12N 1555, C12N 918
Patent
active
052217388
ABSTRACT:
cDNA encoding a human .alpha..sub.2 -plasmin inhibitor precursor protein represented by an amino acid sequence from the -39th Met to the 452nd Lys in FIG. 1 of the accompanying drawings; an amino acid sequence of a human .alpha..sub.2 -plasmin inhibitor precursor represented by an amino acid sequence from the -39th Met to the 452nd Lys in FIG. 1 of the accompanying drawings; and genomic DNA encoding a human .alpha..sub.2 -plasmin inhibitor protein which is composed of exons II, III, IV, V, VI, VII, VIII, IX and X in FIG. 4 of the accompanying drawings, said exons being bonded to one another via introns.
REFERENCES:
Holmes et al., "Primary Structure of Human .alpha..sub.2 -Antiplasmin, a Serine Protease Inhibitor(Serpin)," J. Biol. Chem., 262(4), 1659-1664 (1987).
Sumi et al., "Structure of the Carboxyl-Terminal Half of Human .alpha..sub.2 -Plasmin Inhibitor Deduced from that of cDNA," J. Biochem., 100, 1399-1402 (1986).
Moroi et al., "Isolation and Characterization of .alpha..sub.2 -Plasmin Inhibitor for Human Plasma," J. Biol. Chem., 251(17), 5956-5965 (1976).
Aoki Nobuo
Ichikawa Yataro
Murakami Masami
Sumi Yoshihiko
Brown Johnnie R.
Crane L. Eric
Teijin Limited
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