Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-05-09
2000-01-18
Carlson, Karen Cochrane
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435183, 4353201, 435325, 4352523, 536 232, C12P 2106, C12N 900, C12N 1500, C07H 1700
Patent
active
060156929
ABSTRACT:
The present invention relates to the discovery in mammalian cells, particularly human cells, of a novel CDK-binding protein, referred to herein as "cdc37". As described herein, this protein functions to facilitate activation and accordingly finctions in the modulation of cell-cycle progression, and therefore ultimately of cell growth and differentiation. Moreover, binding data indicated that cdc37 may function coordinately with other cell-cycle regulatory proteins, such as of cyclin-dependent kinases (CDKs), src, p53 and erk kinases.
REFERENCES:
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Draetta Giulio
Gyuris Jeno
Lamphere Lou
Carlson Karen Cochrane
Halstead David P.
Mitotix, Inc.
Vincent, Esq. Matthew P.
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