CD70 inhibition for the treatment and prevention of...

Details CD70 inhibition for the treatment and prevention of... CD70 inhibition for the treatment and prevention of...

2005-02-08

2009-11-10

Ouspenski, Ilia (Department: 1644)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reexamination Certificate

active

07615211

ABSTRACT:
Substantially purified populations of APCLPcells capable of expressing CD70 are described. Also described are methods for the treatment of certain diseases and medical conditions of the gastrointestinal tract, such as inflammatory bowel disease, by utilizing inhibitors of CD70 activity.

REFERENCES:
patent: 2006/0233794 (2006-10-01), Law et al.
Huang Z., Pharmacology and Therapeutics, 2000, 86: 201-215.
Blazar et al., J. Immunol., 1996, 157: 3250-3259.
Borst et al., Current Opinion in Immunology, 2005, 17: 275-281.
Monika Manocha, Svend Rietdijk, Amale Laouar, Atul Bhan, Cox Terhost and Manjunath N. Swamy (2008) The FASEB Journal 22:859.10 (Abstract included).

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