CD4+ T-lymphocyte proteases and genes encoding said proteases

Details CD4+ T-lymphocyte proteases and genes encoding said proteases CD4+ T-lymphocyte proteases and genes encoding said proteases

1995-09-08

1999-02-02

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435226, 435975, C12Q 137, C12N 964

Patent

active

058663517

ABSTRACT:
The present invention includes the identification and isolation of a nucleic acid molecule encoding a dibasic amino acid processing endoprotease from CD4+ T-lymphocytes as well as a protein encoded by that nucleic acid molecule. The present invention also includes related nucleic acid molecules and proteins encoded by such nucleic acid molecules as well as recombinant molecules and recombinant cells that include nucleic acid molecules of the present invention. The present invention also includes use of such nucleic acid molecules and proteins to develop therapeutic compositions that enhance or inhibit dibasic amino acid processing endoprotease activity.

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