CD4+ T-lymphocyte protease genes and inhibitors thereof

Details CD4+ T-lymphocyte protease genes and inhibitors thereof CD4+ T-lymphocyte protease genes and inhibitors thereof

1997-11-24

1999-11-09

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

435325, 4352523, 514 44, 536 245, C12N 1574, C12N 1580, C12N 1585, A61K 3170

Patent

active

059812591

ABSTRACT:
The present invention includes the identification and isolation of a nucleic acid molecule encoding a dibasic amino acid processing endoprotease from CD4+ T-lymphocytes as well as a protein encoded by that nucleic acid molecule. The present invention also includes related nucleic acid molecules and proteins encoded by such nucleic acid molecules as well as recombinant molecules and recombinant cells that include nucleic acid molecules of the present invention. The present invention also includes use of such nucleic acid molecules and proteins to develop therapeutic compositions that enhance or inhibit dibasic amino acid processing endoprotease activity.

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