CD4+CD25− T cells and Tr1-like regulatory T cells

Details CD4+CD25− T cells and Tr1-like regulatory T cells CD4+CD25− T cells and Tr1-like regulatory T cells

2007-06-20

2011-12-13

Juedes, Amy (Department: 1644)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Primate cell, per se

C435S373000, C424S093710

Reexamination Certificate

active

08076134

ABSTRACT:
The invention provides CD4+CD25−T cells and Tr1-like regulatory T cells (i.e., contact-independent Type 1-like regulatory T cells), processes for their production and their use for regulatory purposes.

REFERENCES:
patent: 5721910 (1998-02-01), Unger et al.
patent: 5752020 (1998-05-01), Ando
patent: 5950214 (1999-09-01), Rivette et al.
patent: 5991751 (1999-11-01), Rivette et al.
patent: 5991780 (1999-11-01), Rivette et al.
patent: 5999907 (1999-12-01), Donner
patent: 6014663 (2000-01-01), Rivete et al.
patent: 6038561 (2000-03-01), Snyder et al.
patent: 6534055 (2003-03-01), June et al.
patent: 6803036 (2004-10-01), Horwitz
patent: 7479269 (2009-01-01), June et al.
patent: 2001/0003746 (2001-06-01), Sodemann
patent: 2001/0003950 (2001-06-01), Zhang et al.
patent: 2002/0090357 (2002-07-01), Barrat et al.
patent: 2003/0005085 (2003-01-01), Matsuno
patent: 2003/0013540 (2003-01-01), Penrose
patent: 2003/0014491 (2003-01-01), Horvitz et al.
patent: 0 380 362 (1990-08-01), None
patent: 1 379 625 (2004-01-01), None
patent: 1 409 650 (2006-04-01), None
patent: 91 00345 (1991-01-01), None
patent: 92 11348 (1992-07-01), None
patent: 93 02108 (1993-02-01), None
patent: 95 07991 (1995-03-01), None
patent: 96 09396 (1996-03-01), None
patent: 98 56417 (1998-12-01), None
patent: 00 42856 (2000-07-01), None
patent: 02 097070 (2002-12-01), None
Takahata et al., 2004, Exp. Hem. vol. 32: 622-629.
Levings et al., May 2001, J. Immunol. vol. 166: 5530-5539.
Groux et al., 1997, Nature, vol. 389: 737-742.
Lechler et al., 2001, Phil. Trans. R. Soc. Lond. vol. 356: 625-637.
Chen et al., 2003, J. Exp. Med. vol. 198: 1875-1886.
Dickmann D. et al; “Human CD4+CD25+ Regulatory, Contact-dependent T Cells Induce Interleukin 10-producing, Contact-independent Type 1-like Regulatory T Cells”; The Journal of Experimental Medicine, vol. 196, No. 2; Jul. 15, 2002; pp. 247-253; XP002239198.
Taylor et al, “T regulatory cells and allergy”. Microbes and Infection 2005; 7: 1049-1055.
Thorn et al; “CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation invitro by inhibiting interleukin 2 production”. The Journal of Exp. Med. 1998; 188: 227-296.
Huang Z.; “Structural chemistry and therapeutic intervention of protein-protein interactions in immune response, human immunodeficiency virus entry, and apoptosis.”; Pharmacol Ther. Jun. 2000; 86(3) : 201-15.
Metler et al; “Solution structure of human CTLAM and delineation of a CD80/CD86 binding site conserved in CD28.” Nat. Struct. biol. Jul. 1997; 4(7): 527-31.
Brode et al., Journal of Cellular Biochemistry, vol. 15, Part G., Apr. 8, 1991, p. 205.
De Jong et al; “Differential effect of transforming growth factor-β1 on the activation of human naive and memory CD4+ T lymphocytes,” International Immunology, vol. 6, No. 4, pp. 631-638 (Jan. 1994).
Jonuleit et al; “Induction of Interleukin 10-producing, Nonproliferating CD4+ T Cells with Regulatory Properties by Repetitive Stimulation with Allogeneic Immature Human Dendritic Cells,” J. Exp. Med., vol. 192, No. 9, pp. 1213-1222 (Nov. 6, 2000).
Shimizu et al; “Induction of tumor immunity by removing CD25+CD4+ regulatory T cells: A common basis between tumor immunity and autoimmunity,”; J. Immunol., vol. 163, No. 10, pp. 5211-5218 (1999).
Takahashi et al., “Immunologic self-tolerance maintained by CD25+CD4+ regulatory T cells consitutively expressing cytotoxic T lymphocyte-associated antigen 4”; J. Exp. Med. vol. 192, No. 2, pp. 303-309 (Jul. 17, 2000).
Levings, M. et al., J. Exp. Med., 193: 1295-1301 (2001)01).
Fujimaki, W. et al., Clin. Develop. Immunol., 2008: 1-12 (2008).
Ng, W. et al., BSI Congress 2000, vol. 101, Supplement 1, Abstract 3.12 (2000).
Taams, L. et al., BSI Congress 2000, vol. 101, Supplement 1, Abstract IS6 (2000).
Ng. W. et al., Blood, 98: 2736-2744 (2001).
Taams, L. et al., Eur. J. Immunol., 31: 1122-1131 (2001).
Horwitz, D. et al., Arthrit. Research, 4: 241-246 (2002).
Read, S. et al., J. Exp. Med., 192: 295-302 (2000).
Olivares-Villagomez, D. et al., J. Immunol., 164: 5499-5507 (2000).
Sakaguchi, S., Cell, 101: 455-458 (2000).
Stephens, L. et al., Eur. J. Immunol., 31: 1247-1254 (2001).
Nagahama, K. et al., Methods Molecul. Biol., 380: 431-442 (2007).
Stout et al, 1993, J. Immunol. vol. 150: 5330-5337.
Milteny product information, CD25 microbeads, 2007, pp. 1-3.
Koulis et al, Feb. 2001, Allergy Clin Immunol. vol. 107, p. S294-S295.
Nakamura et al., 2001, J. Exp. Med. vol. 194: 629-644.
Jonuleit et al., Jul. 15, 2002, J. Exp. Med., vol. 196: 255-260.
Baecher-Allan et al., 2001, J. Immunol., vol. 167: 1245-1253.
Office Action issued on May 5, 2006 for corresponding U.S. Appl. No. 10/661,804.
Office Action issued on Nov. 30, 2006 for corresponding U.S. Appl. No. 10/661,804.
Office Action issued on Mar. 15, 2007 for corresponding U.S. Appl. No. 10/661,804.
Office Action issued on Aug. 8, 2007 for corresponding U.S. Appl. No. 10/661,804.
Office Action issued on Mar. 31, 2008 for corresponding U.S. Appl. No. 10/661,804.
Office Action issued on May 22, 2009 for corresponding U.S. Appl. No. 10/661,804.
Office Action issued on Apr. 20, 2006 for corresponding U.S. Appl. No. 10/618,134.
Office Action issued on Dec. 21, 2006 for corresponding U.S. Appl. No. 10/618,134.
Office Action issued on Aug. 7, 2007 for corresponding U.S. Appl. No. 10/618,134.
Office Action issued on Jul. 1, 2008 for corresponding U.S. Appl. No. 10/618,134.
Office Action issued on Mar. 16, 2009 for corresponding U.S. Appl. No. 10/618,134.
Taylor et al, Immunology and Cell Biology (2001) 79, 358-367.
Bacchetta et al., “High levels of interleukin-10 production in vivo are associated with tolerance in SCID patients . . . ,” J. Exp. Med. (1994) pp. 493-502, vol. 179.
Cottrez et al., “Specialization in tolerance: innate CD(4+) CD(25+) versus acquired TR1 and TH3 regulatory cells,” Transplantation (2004) pp. S12-S16, vol. 77.
Dieckmann et al., “Ex vivo isolation and characterization of CD4+ CD25+ T cells with regulatory properties from human blood,” J. Exp. Med. (2001) pp. 1303-1310, vol. 193.
Jackson et al., “Restricted expression of p55 interleukin 2 receptor (CD25) on normal T cells,” Immunol. Immunopathol. (1990) pp. 126-133, vol. 54.
Kanegane et al., “A novel subpopulation of CD45RA+ CD4+ T cells expressing IL-2 . . . ,” Int. Immunol. (1991) pp. 1349-1356, vol. 3.
Rohowsky-Kochan et al., “Cytokine secretion profile of myelin basic protein-specific T cells in multiple sclerosis,” Multiple Sclerosis (2000) pp. 69-77, vol. 6.
Thornton et al., “Suppressor Effector Function of CD4+ CD25+ Immunoregulatory T Cells . . . ,” J. Immunol. (2000) pp. 183-190, vol. 164.
Jago et al., “Differential expression of CTLA-4 among T cell subsets,” Clin. Exp. Immunol. (2004) pp. 463-471, vol. 136.
Leung et al., “Cytotoxic T lymphocyte-associated molecule-4, a high avidity receptor . . . ,” J. Biol. Chem. (1995) pp. 25107-25114, vol. 270.
Office Action mailed Feb. 19, 2010, for copending U.S. Appl. No. 10/661,804.
Office Action mailed Oct. 15, 2009, for copending U.S. Appl. No. 10/618,134.
Office Action mailed Feb. 3, 2010, for copending U.S. Appl. No. 10/618,134.
Office Action mailed Mar. 16, 2010, for copending U.S. Appl. No. 10/618,134.
Alberts et al., eds., Molecular Biology of the Cell, 3rd edition (1994), pp. 142, 157, 158, 748, 749, and 853 (Garland Publishing, Inc., New York, NY, USA).
Ferlin et al., “Present difficulties and future promise of MHC multimers in autoimmune exploration,” Curr. Opin. Immunol. (2000) pp. 670-675, vol. 12.
Goldsby et al., eds., Kuby Immunology, 4th edition (2000), pp. 203-206 and 513 (W.H. Freeman and Co., New York, NY).
Haskins et al., “The major histocompatibility complex-restricted antigen receptor on T cells,” J. Exp. Med. (1983) pp. 1149-1169, vol. 157.
Mestas and Hughes, “Of mice and not men: differences between mouse an

Affiliated with

Also associated with

Rating

CD4+CD25− T cells and Tr1-like regulatory T cells does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with CD4+CD25− T cells and Tr1-like regulatory T cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and CD4+CD25− T cells and Tr1-like regulatory T cells will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4261256