Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1994-04-12
1996-01-02
Draper, Garnette D.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 695, 435 697, 4352401, 4352523, 4353201, 530351, C07H 2104, C12N 1519, C12N 1563, C07K 1452, C07K 100
Patent
active
054809819
ABSTRACT:
There is disclosed a polypeptide (CD30-L) and DNA sequences, vectors and transformed host cells useful in providing CD30-L polypeptides. The CD30-L polypeptide binds to the receptor known as CD30, which is expressed on a number of cell types, among which are Hodgkin's Disease tumor cells, large cell anaplastic lymphoma cells, adult T-cell leukemia (T-ALL) cells, and a number of other malignant cell types. CD30-L polypeptides find use as carriers for delivering diagnostic and cytotoxic agents to cells expressing the CD30 receptor.
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Armitage Richard J.
Goodwin Raymond G.
Gruss Hans-Juergen
Smith Craig A.
Anderson Kathryn A.
Draper Garnette D.
Immunex Corporation
Spector Lorraine M.
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