CD3 .zeta. co-associated complex on CD16.sup.- NK cells

Details CD3 .zeta. co-associated complex on CD16.sup.- NK cells CD3 .zeta. co-associated complex on CD16.sup.- NK cells

1990-01-31

1992-06-23

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 724, 436547, 436548, G01N 33567, G01N 3353, G01N 33555

Patent

active

051242516

ABSTRACT:
A novel protein complex is disclosed which is co-associated with CD3.zeta. on CD16.sup.- NK cells. A purified form of the protein complex, a gene encoding the protein complex and method of producing the purified protein complex also are disclosed. Antibodies that bind to the protein complex and methods for their use further are disclosed.

REFERENCES:
Allison et al., Ann. Rev. Immunol. 5:503-540, 1987.
Clevers et al., Eur. J. Immunol. 18:705-710, 1988.

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