Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Reexamination Certificate
2005-05-24
2005-05-24
Russel, Jeffrey Edwin (Department: 1654)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
C530S345000
Reexamination Certificate
active
06897034
ABSTRACT:
The compounds of the invention are modified forms of therapeutic agents. A typical prodrug compound of the invention comprises a therapeutic agent, an oligopeptide, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by the CD10 enzyme. Methods of treatment using the prodrug and methods of designing a prodrug are also disclosed.
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DATABASE: GenBank, Acc. No. Y00811, Sep. 12, 1993.
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Bebbington Christopher R.
Cardarelli Pina M.
Gangwar Sanjeev
Nieder Matthew H.
Pan Chin
Lahive & Cockfield LLP
Medarex Inc.
Remillard, Esq. Jane E.
Russel Jeffrey Edwin
Soroos, Esq. Cynthia M.
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