Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-07-03
2007-07-03
Balasubramanan, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S247000, C514S256000, C514S336000, C546S314000, C546S315000, C546S268100, C544S224000, C544S335000, C544S333000, C544S405000, C544S406000
Reexamination Certificate
active
10443155
ABSTRACT:
The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.
REFERENCES:
patent: 5541186 (1996-07-01), Breu et al.
patent: 5589478 (1996-12-01), Yamada et al.
patent: 6136971 (2000-10-01), Harrington et al.
patent: 6939885 (2005-09-01), Ungashe et al.
patent: 2005/0137193 (2005-06-01), Ungashe et al.
patent: WO 05/112925 (2005-12-01), None
West, Anthony R., Solid State Chemistry and its Applications, Wiley, New York, 1988, pp. 358 & 365.
Vippagunta et al., Advanced Drug Delivery Reviews 48: 3-26, 2001.
Kelsall et al. Immunol. Rev. 20691): 132-148, 2005.
Yu et al. J. Immunol. 164(3): 1293-1305, 2000.
Hatse et al. FEBS Letters 527255-262, 2002.
Street et al. Journal of Chemical Research, Synopses, 5: 154-155, 1987. CA 108:37599,1988.
Hatoum et al., Ann. N.Y. Acad. Sci. 1072: 78-97, 2006.
Street, Jonathan D., et al., “Cyclising Nucleophilic Addition to Azinium Systems. Part 2. Reactions of 3-Acylpyridinium Hydrazones,”Journal of Chemical Research(S) (1987) pp. 154-155.
Dannhardt, Gerd, et al., “COX-1/COX-2 inhibitors based on the methanone moiety,”European Journal of Medicinal Chemistry, vol. 37 (Feb. 2002) pp. 147-161.
Supplementary European search report issued Feb. 1, 2006 in European Application No. EP 03755422.7, which corresponds to U.S. Appl. No. 10/443,155.
Chen Shaowu
Fleming Paul
Harriman Geraldine C. B.
Shi Zhan
Balasubramanan Venkataraman
Millennium Pharmaceuticals Inc.
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