CCR5 chemokine receptor-specific antibodies

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387100, C530S387900, C530S388100, C530S388150

Reexamination Certificate

active

06930174

ABSTRACT:
A peptide has an amino acid sequence having more than 80% homology with the amino acid sequence listed as SEQ ID NO:4. A nucleic acid molecule has more than 80% homology with one of the nucleic acid sequences listed as SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3. Ligands, anti-ligands, cells vectors relating to the peptide and/or nucleic acid molecule are also used.

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Samson et al. (1996)Molecular Cloning and Functional Expression of a New Human CC-Chemokine Receptor Gene, Biochemistry 35:3362-3367.
Dragic et al. (Jun. 20, 1996)HIV Entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5Nature 381:667-73.
Deng et al. (Jun. 20, 1996)Identification of a major co-receptor for primary isolates of HIV-1, Nature 381:661-6.
International Search Report PCT BE 97/00023.

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