CC-chemokine binding tick proteins

Details CC-chemokine binding tick proteins CC-chemokine binding tick proteins

2005-12-19

2009-12-22

Saoud, Christine J (Department: 1647)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S071100, C435S252300, C435S320100, C435S069500, C514S002600, C514S012200, C530S350000, C536S023400, C536S023500

Reexamination Certificate

active

07635576

ABSTRACT:
A novel CC-chemokine binding protein is isolated from the saliva ofRhipicephalus sanguineus. Compounds prepared in accordance with the present invention can be used as anti-inflammatory compounds and in the treatment or prevention of CC-chemokine-related diseases.

REFERENCES:
Ferreira, B. R. et al. “Antigens fromRhipicephalus sanguineusTicks Elicit Potent Cell-Mediated Immune Responses in Resistant but Not in Susceptible Animals”,Veterinary Parasitology, 2003, pp. 35-48, vol. 115, No. 1.
Hajnická, V. et al. “Anti-interleukin-8 Activity of Tick Salivary Gland Extracts”,Parasite Immunology, 2001, pp. 483-489, vol. 23, No. 9.
Database EMBL [Online], EBI Database Accession No. EM—PRO:CK176525, Jul. 2, 2004, XP-002351500, pp. 1-2.
Database EMBL [Online], EBI Database Accession No. EM—PRO:CK179985, Jul. 2, 2004, XP-002351501, pp. 1-2.
Database UniProt [Online], EBI Database Accession No. UniProt:Q7PM27, Mar. 1, 2004, XP-002351499, pp. 1-2.
Database UniProt [Online], EBI Database Accession No. UniProt:Q626N0, Oct. 25, 2004, XP-002351498, pp. 1-2.
Kocakova, P. et al. “Effect of fast protein liquid chromatography fractionated salivary gland extracts from different ixodid tick species on interleukin-8 binding to its cell receptors”Folia parasitologica, 2003, pp. 79-84, vol. 50.

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