Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-11-21
1999-02-09
Hutzell, Paula K.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352542, 43525411, 43525422, 4352573, 4353701, 536 231, 536 234, 536 235, 536 2431, 530350, 530824, 4242741, 935 1, 935 19, C12N 1500, C07K 1400
Patent
active
058692908
ABSTRACT:
The invention provides caYAE1 polypeptides and DNA (RNA) encoding such caYAE1 and a procedure for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such caYAE1 for the treatment of infection, particularly fungal infections. Antagonists against such caYAE1 and their use as a therapeutic to treat infections, particularly fungal infections are also provided. Further provided are diagnostic assays for detecting diseases related to the presence of caYAE1 nucleic acid sequences and the polypeptides in a host. Also provided are diagnostic assays for detecting polynucleotides encoding caYAE1 and for detecting the polypeptide in a host.
REFERENCES:
patent: 4879213 (1989-11-01), Fox et al.
patent: 5405745 (1995-04-01), Goman et al.
patent: 5529916 (1996-06-01), Cormack et al.
EMBO Journal, 15:2031-2049, 1996.
scYAE1 homologue sequence fragment, The homepage of the Candida albicans information pages on the Alces WWW server, located at : http://alces.med.umn.edu/Candida.html available from the mapping project at the University of Minnesota.
Zha et al. Eur. J. Biochem. 1992, vol. 207, 305-313.
Lehniyan Biochemistry, new Ed. 1975, p. 63, Neonh Publishers, Inc., New York, N.Y.
Bringen et al. J. Cel Biol. 1990 vol. 111, 2129-2138.
Lazan et al. Mol. Cel. Biol. 1988, vol. 8 No. 3, 1247-1252.
Freeman Kathryn Belinda
Livi George Pietro
Nicholas Richard Oakley
Gimmi Edward R.
Hutzell Paula K.
King William T.
Masood Khalzd
SmithKline Beecham Corporation
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