Cationized polysaccharide derivatives with hypocholesterolemic a

Details Cationized polysaccharide derivatives with hypocholesterolemic a Cationized polysaccharide derivatives with hypocholesterolemic a

1991-02-05

1991-10-22

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 172, 536 179, 536 185, 536 187, 536 20, 536 30, 536 22, 536 45, 536 52, 536 55, 536 552, 536 553, C07H 100, C07H 500, C08B 3700, C08B 3100

Patent

active

050596853

ABSTRACT:
Cationized derivatives of natural polysaccharides having a polyglucoside structure with 50-5000 monomer units and one or more side chains bonded to the glucoside nucleus by a nitrogen or oxygen atom or an amide group, said side chains having one or more quaternary nitrogen atoms so that each monomer unit has a cation charge density exceeding two. The new compounds are particularly active as hypocholesterolemic agents.

REFERENCES:
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patent: 4411891 (1983-10-01), Mizutani et al.
patent: 4436731 (1984-03-01), Maltz
patent: 4663159 (1987-05-01), Brode, II et al.
patent: 4772690 (1988-09-01), Lang et al.
patent: 4921949 (1990-05-01), Lang et al.
Patent Abstracts of Japan, vol. 10, No. 226 (Aug. 7, 1986).
Chemical Abstracts, vol. 109, Abstract No. 204924h (Dec. 5, 1988).

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