Cationic technetium complexes useful as radiodiagnostic agents

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...

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534 14, 556 1, 556 13, 556 17, 556 18, 556 19, 556 30, 556 64, 556 81, 568 2, 568 8, 568 13, 568 14, 568 15, 568 16, 568 17, 424 9, A61K 4300, A61K 4900

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RE0328260

ABSTRACT:
A cationic lipophilic complex of technetium is disclosed wherein all of the coordination positions of the technetium atom are filled with a neutral donor atom having a pair of electrons available for forming a coordinate bond with technetium. The donor atoms are provided by target-seeking ligands or salts thereof, said ligands having the following structure of one of formulas I, II or III. Such complexes are useful for imaging heart and hepatobiliary tissues.

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